Evangelia Charmandari Selected Research

Glucocorticoid Receptors (Glucocorticoid Receptor)

1/2019	Glucocorticoid Resistance.
12/2017	Increased glucocorticoid receptor expression in sepsis is related to heat shock proteins, cytokines, and cortisol and is associated with increased mortality.
4/2016	Sequencing analysis of the human glucocorticoid receptor (NR3C1) gene in multiple sclerosis patients.
2/2016	Structural Analysis on the Pathologic Mutant Glucocorticoid Receptor Ligand-Binding Domains.
1/2016	Recent advances in the molecular mechanisms causing primary generalized glucocorticoid resistance.
5/2015	Chrousos syndrome: from molecular pathogenesis to therapeutic management.
5/2014	A novel point mutation of the human glucocorticoid receptor gene causes primary generalized glucocorticoid resistance through impaired interaction with the LXXLL motif of the p160 coactivators: dissociation of the transactivating and transreppressive activities.
4/2013	A novel point mutation in the DNA-binding domain (DBD) of the human glucocorticoid receptor causes primary generalized glucocorticoid resistance by disrupting the hydrophobic structure of its DBD.
10/2007	A novel point mutation in helix 11 of the ligand-binding domain of the human glucocorticoid receptor gene causing generalized glucocorticoid resistance.
4/2006	Functional characterization of the natural human glucocorticoid receptor (hGR) mutants hGRalphaR477H and hGRalphaG679S associated with generalized glucocorticoid resistance.

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Evangelia Charmandari Research Topics

Disease

20	Glucocorticoid Receptor Deficiency 01/2019 - 09/2002
12	Hyperandrogenism 05/2015 - 05/2002
11	Congenital Adrenal Hyperplasia (Hyperplasia, Congenital Adrenal) 01/2017 - 05/2002
9	Hypersensitivity (Allergy) 04/2017 - 06/2003
7	Insulin Resistance 08/2021 - 05/2002
7	Obesity 08/2021 - 05/2003
7	Congenital adrenal hyperplasia due to 21 hydroxylase deficiency 01/2017 - 05/2002
6	Hypertension (High Blood Pressure) 03/2021 - 09/2002
5	Metabolic Syndrome (Dysmetabolic Syndrome X) 06/2021 - 05/2002
4	Overweight 04/2021 - 12/2011
4	Hyperaldosteronism (Conn Syndrome) 03/2021 - 08/2012
4	Cushing Syndrome 05/2014 - 07/2002
3	Inflammation (Inflammations) 09/2021 - 04/2016
3	Infections 01/2021 - 06/2003
2	Neoplasms (Cancer) 06/2022 - 02/2022
2	Precocious Puberty 09/2021 - 01/2019
2	Adenoma (Adenomas) 03/2021 - 12/2016
2	Adrenal Insufficiency (Adrenal Gland Hypofunction) 01/2021 - 06/2014
2	Polycystic Ovary Syndrome (Syndrome, Stein-Leventhal) 10/2017 - 05/2002
2	Inborn Genetic Diseases (Disease, Hereditary) 05/2014 - 10/2012
2	Fatigue 05/2008 - 04/2004
1	Hypothyroidism 06/2022
1	Hypogonadism (Hypergonadotropic Hypogonadism) 06/2022
1	Prolactinoma (Prolactinomas) 06/2022
1	Hyperprolactinemia 06/2022
1	Uterine Cervical Neoplasms (Cancer of the Cervix) 02/2022
1	Breast Neoplasms (Breast Cancer) 02/2022
1	Infertility (Sterility) 02/2022
1	Mood Disorders (Mood Disorder) 05/2021
1	Post-Traumatic Stress Disorders (Post Traumatic Stress Disorder) 05/2021
1	Schizophrenia (Dementia Praecox) 05/2021
1	Malnutrition (Nutritional Deficiencies) 01/2021
1	Ischemia 01/2021
1	COVID-19 01/2021
1	Fibrosis (Cirrhosis) 01/2021
1	Diabetes Mellitus 01/2021
1	Genomic Instability 12/2019
1	Lymphoproliferative Disorders (Lymphoproliferative Disorder) 08/2019
1	Parkinson Disease (Parkinson's Disease) 08/2019
1	Systemic Inflammatory Response Syndrome (Sepsis Syndrome) 12/2017
1	Sepsis (Septicemia) 12/2017

Drug/Important Bio-Agent (IBA)

27	GlucocorticoidsIBA 06/2021 - 05/2002
18	Hydrocortisone (Cortisol)FDA LinkGeneric 01/2019 - 05/2002
14	Glucocorticoid Receptors (Glucocorticoid Receptor)IBA 01/2019 - 06/2003
10	Adrenocorticotropic Hormone (ACTH)FDA Link 12/2017 - 05/2004
10	MineralocorticoidsIBA 06/2014 - 05/2002
8	AldosteroneIBA 03/2021 - 05/2002
6	SteroidsIBA 12/2017 - 09/2002
5	Proteins (Proteins, Gene)FDA Link 12/2017 - 09/2002
5	Insulin (Novolin)FDA Link 10/2017 - 05/2002
4	Hormones (Hormone)IBA 06/2022 - 06/2014
4	LigandsIBA 01/2016 - 06/2005
4	AndrogensIBA 06/2014 - 05/2002
4	SaltsIBA 01/2005 - 07/2002
3	Triglycerides (Triacylglycerol)IBA 01/2021 - 10/2017
3	Protein Isoforms (Isoforms)IBA 12/2017 - 07/2004
3	glucocorticoid receptor alphaIBA 04/2006 - 04/2004
2	ProlactinIBA 06/2022 - 12/2017
2	Gonadotropin-Releasing Hormone (GnRH)FDA Link 02/2022 - 09/2021
2	EnzymesIBA 08/2021 - 11/2004
2	Biomarkers (Surrogate Marker)IBA 04/2021 - 07/2002
2	LeptinIBA 01/2021 - 05/2002
2	ApolipoproteinsIBA 01/2019 - 12/2011
2	CytokinesIBA 12/2017 - 04/2016
2	Glucose (Dextrose)FDA LinkGeneric 10/2017 - 02/2004
2	Amino Acids FDA Link 01/2016 - 09/2002
2	Isoleucine (L-Isoleucine)FDA Link 01/2016 - 09/2002
2	Epinephrine (Adrenaline)FDA LinkGeneric 08/2004 - 02/2004
1	Growth Hormone (Somatotropin)IBA 06/2022
1	Cabergoline FDA LinkGeneric 06/2022
1	Alkylating AgentsIBA 02/2022
1	Nerve Growth Factors (Neurotrophins)IBA 09/2021
1	ProstaglandinsIBA 09/2021
1	LipidsIBA 08/2021
1	Glycated Hemoglobin (Glycosylated Hemoglobin)IBA 08/2021
1	AdipokinesIBA 07/2021
1	fibroblast growth factor 21IBA 04/2021
1	Ion Channels (Ion Channel)IBA 03/2021
1	Contrast MediaIBA 01/2021
1	Pro-Opiomelanocortin (Proopiomelanocortin)IBA 01/2021
1	Glucagon-Like Peptide ReceptorsIBA 01/2021
1	GadoliniumIBA 01/2021
1	Adenosine (Adenocard)FDA LinkGeneric 01/2021
1	NucleoproteinsIBA 12/2019
1	SynucleinsIBA 08/2019
1	B-insulinIBA 01/2019
1	Heat-Shock Proteins (Heat-Shock Protein)IBA 12/2017
1	InterleukinsIBA 12/2017
1	Messenger RNA (mRNA)IBA 12/2017
1	CholesterolIBA 10/2017
1	Vitamin D FDA LinkGeneric 10/2017
1	25-hydroxyvitamin DIBA 10/2017
1	LDL CholesterolIBA 10/2017
1	Testosterone (Sustanon)FDA Link 10/2017
1	CalciumIBA 10/2017

Therapy/Procedure

6	Therapeutics 02/2022 - 07/2002
1	Craniotomy 06/2022
1	Drug Therapy (Chemotherapy) 02/2022
1	Radiotherapy 02/2022
1	Obesity Management 01/2021